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We are in relentless pursuit of breakthroughs that improve patients' lives. We drive innovation each day to make the world a more healthy place. It was Charles Pfizer's original vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best professionals, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and shows our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and represents the value we strive to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We embody our purpose by seeking the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.